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Spectrum of Serious Neurological and Psychiatric Adverse Events in Indian COVID-19 Vaccine Recipients: A Systematic Review of Case Reports and Case Series
Neurol India. 2023 Mar-Apr;71(2):209-227. doi: 10.4103/0028-3886.375420.ABSTRACTIndian data regarding serious neurological and psychiatric adverse events, following coronavirus disease 2019 (COVID-19) vaccination, are lacking. We, therefore, systematically evaluated cases of post-vaccinal serious neurological and psychiatric adverse reactions published from India. A systematic review of cases published from India, which were archived in PubMed, Scopus, and Google Scholar databases, was performed; pre-print databases along with ahead-of-print contents were searched in addition. Retrieved articles, as on June 27, 2022, were ...
Source: Herpes - May 6, 2023 Category: Infectious Diseases Authors: Ravindra Kumar Garg Vimal Paliwal Hardeep Singh Malhotra Balendra Pratap Singh Imran Rizvi Neeraj Kumar Source Type: research

Biological drugs for systemic lupus erythematosus or active lupus nephritis and rates of infectious complications. Evidence from large clinical trials
Front Immunol. 2022 Sep 23;13:999704. doi: 10.3389/fimmu.2022.999704. eCollection 2022.ABSTRACTSystemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that frequently affects the kidneys, known as lupus nephritis (LN). Such patients are treated with antimalarials, corticosteroids or immunosuppressive drugs, and more recently, target-specific biological drugs. Although efficacy of these therapies improved SLE-related outcomes, SLE remains associated with higher rates of infections. Here, we performed a comprehensive systemic review of infectious complications in clinical trials covering drug interventions f...
Source: Herpes - October 10, 2022 Category: Infectious Diseases Authors: Stefanie Steiger Louisa Ehreiser Juliane Anders Hans-Joachim Anders Source Type: research

40 Years after the Registration of Acyclovir: Do We Need New Anti-Herpetic Drugs?
We present the most important anti-herpesviral agents, the mechanisms of resistance to these drugs, and the associated mutations in the viral genome. Special emphasis was placed on newly introduced drugs such as maribavir and brincidofovir. We also briefly discuss the most promising substances in preclinical testing as well as immunotherapy options and vaccines currently in use and under investigation.PMID:35408788 | PMC:PMC8998721 | DOI:10.3390/ijms23073431
Source: Herpes - April 12, 2022 Category: Infectious Diseases Authors: Anna Majewska Beata Mlynarczyk-Bonikowska Source Type: research

Herpes zoster in patients with solid tumors treated with immune checkpoint inhibitors
Immunotherapy. 2022 Feb 14. doi: 10.2217/imt-2021-0333. Online ahead of print.ABSTRACTTweetable abstract Herpes zoster (HZ) is a vaccine-preventable disease, but the role of the vaccine in cancer patients during immunotherapy (ICIs) is still unknown. The clinical and economic consequences of HZ and the increased use of ICIs require a greater awareness by the oncologist.PMID:35152721 | DOI:10.2217/imt-2021-0333
Source: Herpes - February 14, 2022 Category: Infectious Diseases Authors: Francesco Serra Irene Cassaniti Daniele Lilleri Paolo Pedrazzoli Fausto Baldanti Angioletta Lasagna Source Type: research